Product Name: L1CAM antibody [1J36]
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: L1 cell adhesion molecule
Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq, Jul 2008]
Synonyms: SPG1 Antibody , HSAS Antibody , N-CAM-L1 Antibody , CAML1 Antibody , MASA Antibody , N-CAML1 Antibody , S10 Antibody , CD171 Antibody , L1 cell adhesion molecule Antibody , HSAS1 Antibody , MIC5 Antibody , L1CAM Antibody
Cellular Localization:
CAS NO: 18010-40-7
Product: Bephenium
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Human recombinant NCAM-L1 EC domain
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to specifically detect human L1ACM
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23260146?dopt=Abstract
