Product Name: L1CAM antibody [UJ181.4]
Applications: IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied:
Concentration: 0.6 mg/ml (Please refer to the vial label for the specific concentration)
Purification: IgG fraction
Full Name: L1 cell adhesion molecule
Background: The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.
Synonyms: S10, CD171, HSAS1, MIC5, L1 cell adhesion molecule, L1CAM, antigen identified by monoclonal antibody R1, SPG1, NEURAL CELL ADHESION MOLECULE L1 PRECURSOR, MASA, N CAML1, HGNC:7086, CAML1, HSAS, N-CAM-L1, N-CAML1, NCAM-L1, NCAM L1, N CAM L1, NCAML1
Cellular Localization: Cell Membrane
CAS NO: 71963-77-4
Product: Sanguinarine
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Tissue / cell preparation. 16 week human foetal brain.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Preservative: None. Constituents: PBS
Storage Instruction: Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/28387729?dopt=Abstract
