Product Name: Lactate Dehydrogenase antibody (HRP)
Applications: ELISA, ICC/IF, IHC, IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: IgG fraction
Full Name:
Background: Lactate dehydrogenase (LDH) is present in a wide variety of organisms, including plants and animals. It is an oxidoreductase which catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called Hydroxybutyrate Dehydrogenase (HBD). There are 5 different isoenzymes of LDH, LDH-1 to LDH-5, each composed of 4 subunits which may be of 2 different types – M and H subunits. These subunits are encoded by two different genes: The M subunit is encoded by gene LDHA whilst the H subunit is encoded by LDHB. Usually LDH-2 is the predominant form in the serum. An LDH-1 level higher than the LDH-2 level suggests myocardial infarction (damage to heart tissues releases heart LDH, which is rich in LDH-1, into the bloodstream).
Synonyms: LDHM
Cellular Localization: Cytoplasmic
CAS NO: 13189-98-5
Product: Peimisine
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: Full length native Lactate Dehydrogenase (purified)
Antigen Species:
Species Reactivity: Human, Mouse, Rabbit
Conjugation: HRP
Storage Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, containing 10 mg/ml Bovine Serum Albumin and 0.01% gentamicin sulfate
Storage Instruction: Store vial at 4° C for short-term use. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Lactate Dehydrogenase [Rabbit Muscle]
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25851903?dopt=Abstract
