Product Name: Lamin B2 antibody [GT144]
Applications: ICC/IF, IHC-P, IP, WB
Predicted Target Size: 68 kDa (note)
Positive Controls: U87-MG , SK-N-SH , IMR32 , SK-N-AS , HepG2 , HepG2 nuclear
Form Supplied: Liquid
Concentration: 0.81 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein G.
Full Name: lamin B2
Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene. [provided by RefSeq]
Synonyms:
Cellular Localization: Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side
CAS NO: 62571-86-2
Product: Telatinib
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: Recombinant protein encompassing a sequence within the center region of human Lamin B2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22171010?dopt=Abstract
