Product Name: Laminin alpha 5 antibody [4C7 (2D8/33)]
Applications: ELISA, ICC/IF, IP
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification:
Full Name: laminin subunit alpha 5
Background: This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
Synonyms: LAMA5 Antibody
Cellular Localization:
CAS NO: 878419-78-4
Product: GDC-0994
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: Purified human laminin
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Ascites with 0.09% Sodium Azide
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody reacts with the globular domain of the alpha-5 chain of intact laminin.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20133703?dopt=Abstract
