Product Name: LAT (phospho Tyr191) antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The antibody was purified by immunogen affinity chromatography.
Full Name: linker for activation of T cells
Background: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms: LAT Antibody , linker for activation of T cells Antibody , LAT1 Antibody , pp36 Antibody
Cellular Localization:
CAS NO: 1177827-73-4
Product: Nepicastat (hydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human LAT. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
Storage Instruction: Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Recognizes endogenous levels of LAT (pY191) protein.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20357360?dopt=Abstract
