Product Name: LAT antibody [LAT-01]
Applications: FACS, IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A purified
Full Name: linker for activation of T cells
Background: Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.
Synonyms: LAT1, pp36
Cellular Localization: Cell Membrane
CAS NO: 1380316-03-9
Product: Mutant IDH1-IN-1
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant fragment (Human). (Entire cytoplasmic domain).
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline pH 7.4 containing 15mM sodium azide
Storage Instruction: Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody does not optimally recognize tyrosine-phosphorylated LAT.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19703463?dopt=Abstract