Product Name: Lck antibody [LCK-01]
Applications: FACS, ICC/IF, IP, WB
Predicted Target Size:
Positive Controls: Jurkat cell lysate
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A purified
Full Name: lymphocyte-specific protein tyrosine kinase
Background: Lck (p56lck), a member of the Src family of non-receptor tyrosine protein kinases, is expressed predominantly in T cells. Lck function is critical both for T cell development in the thymus and activation of mature T cells in the periphery by antigen. The activity of Lck is known to be regulated by phosphorylation of two conserved tyrosine residues, Tyr-505 (equivalent to Tyr-529 in c-Src) and Tyr-394 (equivalent to Tyr-418 in c-Src).
Synonyms: LSK, YT16, p56lck, pp58lck
Cellular Localization: Cytoplasmic
CAS NO: 1168091-68-6
Product: LY2606368 (dihydrochloride)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Synthetic peptide, corresponding to amino acids 22-36 of Human Lck p56.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline pH 7.4 containing 15mM sodium azide
Storage Instruction: Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The antibody recognizes defined epitope (aa 22-36) on p56lck.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27473585?dopt=Abstract
