Product Name: Lck antibody [N3C3]
Applications: WB
Predicted Target Size: 58 kDa (note) (4)
Positive Controls: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji
Form Supplied: Liquid
Concentration: 0.66 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: lymphocyte-specific protein tyrosine kinase
Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq]
Synonyms: LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, LCK antibody, t cell-specific protein-tyrosine kinase antibody, tyrosine-protein kinase Lck antibody, p56(LSTRA) protein-tyrosine kinase antibody, proto-oncogene tyrosine-protein kinase LCK antibody, leukocyte C-terminal Src kinase antibody, T-lymphocyte specific protein tyrosine kinase p56lck antibody, lymphocyte cell-specific protein-tyrosine kinase antibody, lymphocyte-specific protein tyrosine kinase antibody
Cellular Localization: Cytoplasm , Cell membrane; Lipid-anchor; Cytoplasmic side
CAS NO: 1374639-79-8
Product: BMS-983970
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Lck. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27597886?dopt=Abstract
