Product Name: LEF1 antibody, N-term
Applications: WB
Predicted Target Size: 44 KDa (note)
Positive Controls: HeLa
Form Supplied: Liquid
Concentration: 0.5-1 mg/ml
Purification: Affinity Purified
Full Name: lymphoid enhancer binding factor 1
Background: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Synonyms: TCF7L3 Antibody , TCF10 Antibody , LEF1 Antibody , TCF1ALPHA Antibody
Cellular Localization:
CAS NO: 58-93-5
Product: IKK epsilon-IN-1
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: A synthetic peptide corresponding to a N-terminal region of Human LEF1
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18026195?dopt=Abstract
