Product Name: Leptin antibody [9L19]
Applications: Neut, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: leptin
Background: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
Synonyms: leptin Antibody , LEPD Antibody , LEP Antibody , OB Antibody , OBS Antibody
Cellular Localization:
CAS NO: 878141-96-9
Product: ATN-161 (trifluoroacetate salt)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Human recombinant Leptin
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to specifically detect human Leptin.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24569463?dopt=Abstract
