Product Name: Leptin Receptor antibody
Applications: ELISA, IHC, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified
Full Name: leptin receptor
Background: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
Synonyms: OBR Antibody , CD295 Antibody , LEP-R Antibody , OB-R Antibody , leptin receptor Antibody , LEPR Antibody , LEPRD Antibody
Cellular Localization:
CAS NO: 1093100-40-3
Product: K02288
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen:
Antigen Species: Human
Species Reactivity: Human, Mouse, Pig, Rat
Conjugation: Unconjugated
Storage Buffer: 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide
Storage Instruction: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25173091?dopt=Abstract
