Product Name: Leptin Receptor antibody [9L34]
Applications: IHC, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: leptin receptor
Background: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
Synonyms: OBR Antibody , CD295 Antibody , LEP-R Antibody , OB-R Antibody , leptin receptor Antibody , LEPR Antibody , LEPRD Antibody
Cellular Localization:
CAS NO: 22071-15-4
Product: CB-839
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2
Immunogen: Human recombinant Leptin R EC domain
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to detect human Leptin Receptor.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24244864?dopt=Abstract
