Product Name: Leptin Receptor antibody, Internal
Applications: WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX89338-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: leptin receptor
Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.
Synonyms: OBR, CD295, LEPR, Leptin Receptor, OB receptor, LeprB, DKFZp686B1731
Cellular Localization:
CAS NO: 54965-21-8
Product: CUDC-427
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-TQDDIEKHQSDAG
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for Leptin Receptor.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24391944?dopt=Abstract