Product Name: LETM1 antibody
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 83 kDa (note)
Positive Controls: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: leucine zipper-EF-hand containing transmembrane protein 1
Background: This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq]
Synonyms: LETM1 antibody, “LETM1 and EF-hand domain-containing protein 1, mitochondrial antibody”, leucine zipper-EF-hand-containing transmembrane protein 1 antibody, Mdm38 homolog antibody, leucine zipper-EF-hand containing transmembrane protein 1 antibody
Cellular Localization: Mitochondrion inner membrane; Single-pass membrane protein
CAS NO: 616-91-1
Product: H-89 (dihydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human LETM1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21980003?dopt=Abstract