Product Name: LIFR antibody [9B23]
Applications: FACS, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: leukemia inhibitory factor receptor alpha
Background: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms: CD118 Antibody , SJS2 Antibody , LIFR Antibody , LIF-R Antibody , leukemia inhibitory factor receptor alpha Antibody , SWS Antibody , STWS Antibody
Cellular Localization:
CAS NO: 53994-73-3
Product: Bethoxazin
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Human recombinant LIFR alpha EC domain
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to detect human LIFR.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23284858?dopt=Abstract
