Product Name: LILRA2 antibody [N1C2]
Applications: FACS
Predicted Target Size: 53 kDa (note) (5)
Positive Controls: Target recombinant protein
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
Background: Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.[supplied by OMIM]
Synonyms: CD85H antibody, ILT1 antibody, LIR-7 antibody, LIR7 antibody, LILRA2 antibody, leukocyte immunoglobulin-like receptor subfamily A member 2 antibody, leukocyte immunoglobulin-like receptor subfamily A member 2 soluble antibody, leukocyte immunoglobulin-like receptor 7 antibody, CD85 antigen-like family member H antibody, immunoglobulin-like transcript 1 antibody, ILT-1 antibody, “leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 antibody”
Cellular Localization: Membrane; Single-pass type I membrane protein
CAS NO: 22888-70-6
Product: GNE-9605
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human LILRA2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27044324?dopt=Abstract
