Product Name: LILRB3 antibody [N1C1]
Applications: WB
Predicted Target Size: 69 kDa (note) (4)
Positive Controls: Jurkat
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms: CD85A antibody, HL9 antibody, ILT5 antibody, LIR-3 antibody, LIR3 antibody, MGC138403 antibody, PIRB antibody, LILRB3 antibody, leukocyte immunoglobulin-like receptor subfamily B member 3 antibody, leukocyte immunoglobulin-like receptor 3 antibody, monocyte inhibitory receptor HL9 antibody, immunoglobulin-like transcript 5 antibody, CD85 antigen-like family member A antibody, “leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 antibody”
Cellular Localization:
CAS NO: 303-45-7
Product: Valifenalate
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human LILRB3. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27416955?dopt=Abstract
