Product Name: Lipin 1 antibody
Applications: ELISA, ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity chromatography purified via peptide column.
Full Name: lipin 1
Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]
Synonyms: PAP1 Antibody , lipin 1 Antibody
Cellular Localization:
CAS NO: 1421373-66-1
Product: Losmapimod
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Lipin 1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human Lipin 1.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide.
Storage Instruction: Be stored at 4oC for three months and -20oC, stable for up to one year.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: LPIN1 antibody is human reactive. At least four isoforms of Lipin 1 are known to exist.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17376411?dopt=Abstract
