Product Name: LIS1 antibody
Applications: WB
Predicted Target Size:
Positive Controls: NIH-3T3 lysate
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: IgG fraction
Full Name: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Background: This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq]
Synonyms: 5048, PAFAH, LIS1, MDCR, 601545, PAFAH1B1, P43034, LIS2, MDS
Cellular Localization:
CAS NO: 34580-14-8
Product: AGN 195183
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: Peptide with sequence TGSVDQTVKVWECR, from C Terminus of the protein sequence according to NP_000421
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Storage Instruction: Upon receipt – Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23001124?dopt=Abstract
