Product Name: LMAN1 antibody [N1C1]
Applications: IHC-P, WB
Predicted Target Size: 58 kDa (note) (2)
Positive Controls: HeLa , HepG2 , HCT116
Form Supplied: Liquid
Concentration: 0.82 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: lectin, mannose-binding, 1
Background: The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]
Synonyms: ERGIC-53 antibody, ERGIC53 antibody, F5F8D antibody, FMFD1 antibody, MCFD1 antibody, MR60 antibody, gp58 antibody, LMAN1 antibody, endoplasmic reticulum-golgi intermediate compartment protein 53 antibody, protein ERGIC-53 antibody, ER-Golgi intermediate compartment 53 kDa protein antibody, intracellular mannose specific lectin antibody, intracellular mannose-specific lectin MR60 antibody, “lectin, mannose-binding, 1 antibody”
Cellular Localization: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein , Golgi apparatus membrane; Single-pass membrane protein , Endoplasmic reticulum membrane; Single-pass type I membrane protein
CAS NO: 15687-27-1
Product: KX1-004
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human LMAN1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/12488447?dopt=Abstract
