Product Name: LMP2 antibody, C-term
Applications: FACS, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: Batch dependent mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A purified, followed by peptide affinity purification.
Full Name: proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 2S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 2S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq]
Synonyms: Macropain chain 7, Multicatalytic endopeptidase complex chain7, Proteasome chain 7, Low molecular mass protein2, Proteasome subunit beta type9, RING12 protein, Proteasome subunit beta type-9, PSMB9, Low molecular mass protein 2, Multicatalytic endopeptidase complex chain 7, P, Proteasome subunit beta-1i, Proteasome chain7, Proteasome subunit beta1i, Macropain chain7, LMP2, RING12, Proteasome subunit beta 1i, Proteasome subunit beta type 9
Cellular Localization:
CAS NO: 36945-98-9
Product: NMS-1286937
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide between 193-219 amino acids from the C-terminal region of human PSMB9.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS, 0.09% sodium azide.
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26306899?dopt=Abstract
