Product Name: LNX1 antibody, Internal
Applications: ELISA
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: ligand of numb-protein X 1
Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
Synonyms: multi-PDZ-domain-containing protein, MPDZ, PDZRN2, ligand of numbprotein X1, LNX, ligand of numbprotein X 1, multiPDZdomaincontaining protein, LNX1, ligand of numb-protein X 1, ligand of numb protein X 1
Cellular Localization:
CAS NO: 223763-80-2
Product: GBR 12935
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-PDAYRPRDDSFH
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for LNX1.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27504968?dopt=Abstract
