Olism (P = 0.86), but prevalence of low HDL was Chaetocin biological activity significantly higher in Necrostatin-1 dose females than in males (65.4 vs. 35.8 ; P < 0.001). In addition, MeS was not significantly associated with age and duration of HD and was not significantly associated with BUN, Cr, Ca, P, immunoreactive parathyroid hormone (iPTH), Alb, Hb, iron, total iron binding capacity (TIBC), ferritin, C-reactive protein (CRP), and Kt/V.Metabolic Syndrome P ValueYes (n = 151) 70 (46.4) 117 (77.5) 81 (53.6)< 0.0001 < 0.0001 0.88 c 0.007 0.43 c 0.18 cAge, yDiabetes mellitus Hypertension Low HDLC65 [20-90] 130 [80-200] 80 [50-100]65 [36-84] 130 [90-200] 80 [50-110] 106 (70.2) 102 (67.5) 25.2 ?4.2 85 (56.3) 116 (76.8) 135 (89.4)Metabolic features Systolic BP, mm HgDiastolic BP, mm HgAbnormal glucose metabolism Elevated triglycerides Abdominal obesity FBS, mmol/L Body mass index, kg/m2 Cholesterol, mmol/L HDLC, mmol/L Creatinine, mol/L Sodium, mmol/L iPTH, ng/L WBC PLT Calcium, mmol/L Hemoglobin, g/L Fe, mol/L CRP TIBC, mol/L AST, kat/L KT/V ALT, kat/L< 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 0.46 c 0.08 0.245 0.68 0.01 0.82 0.12 0.22 0.17 0.39 cSerum laboratory features4.88 [3.33-24.98] 23.56 [6.78-92.46] 777.92 ?238.68 2.56 ?.42 2.28 ?0.18 139.1 ?3.6 5.3 ?0.8 1.45 [0.43-7.55] 3.82 ?0.86 1.26 ?0.22.9 ?3.6.83 [3.05-21.15] 21.74 [6.07-89.96] 751.40 ?203.32 1.58 ?0.36 2.23 ?0.18 138.5 ?3.4 5.13 ?0.6 1.23 [0.59-5.76] 1.06 ?0.26 4.35 ?1.Triglyceride, mmol/L Potassium, mmol/LBlood urea nitrogen, mmol/LPhosphorus, mmol/L1766 ?109/L (806 ?109/L-6236 ?109/L) 1208.44 [26.90-5605] 0.30 [0.07-1.60] 0.28 [0.12-2.29] 421.75 ?93.39 48 [12-192] 26 (17.4) 14 (31.8) 5 (11.4) 44 21 (14.1) 1.18 ?0.25 41 ?6 20 [0-120] 13.60 [3.40-37.95] 52.57 ?9.108 ?2 6 ?109/L (2.76 ?109/L-12.26 ?109/L)254 [11-2000]107 ?17 6.66 ?109/L (2.56 ?109/L-15.76 ?109/L) 1806 ?109/L (676 ?109/L-5016 ?109/L) 890.07 [29.15-4232.90] 0.28 [0.08-2.29] 410.45 ?83.28 1.24 ?0.24 36 [12-144] 46 (30.5) 10 (17.9) 14 (25) 56 42 (27.8) 39 ?5 0.30 [0.08-3.52] 0 [0-120] 13.96 [4.48-39.56] 49.49 ?11.225.5 [8-1516]0.002 c 0.602 0.056 c 0.075 c 0.738 0.06 0.28 0.47 0.Ferritin, mmol/L Albumin, g/LUric acid, mol/L Duration of treatment with hemodialysis, mo History of MI Death MI History of Stroke Stroke0.412 c 0.004 0.008 0.Nephro Urol Mon. 2015;7(1):e32 (57.1) a Data are presented as mean ?SD or No. ( ) or median [range]. b Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BP, blood pressure; CRP, C-reactive protein; FBG, fasting blood sugar; Fe, iron; GIB, gastrointestinal bleeding; HDLC, high-density lipoprotein cholesterol; iPTH, immunoreactive parathyroid hormone; MI, myocardial infarction; PLT, platelet count; TIBC, total iron binding capacity; WBC, white blood cell. c Mann Whitney U test.Others (Sepsis, Cancer, Cirrhosis, Pneumonia, GIB, unknown)25 (56.8)During the study, the CHD occurred more frequently in patients with MeS (42 patients (27.8 )) than in those without MeS (21 patients (14.1 )) (P = 0.004). The rate of death due to CHD was 28.6 (12 patients) in those with MeS and 23.8 (5 patients) in those without MeS, showing no significant differences (Table 2). In addition,Variables Age, yJalalzadeh M et al.Table 3. Metabolic and Laboratory factors of Hemodialysis Patients by Gender a,bMetabolic syndrome Diabetes mellitus Hypertension Low HDLC Female (n = 127) 62.4 ?13.5 105 (82.7) 83 (65.4) 56 (44.1) 78 (61.4) 65 (51.2) 81 (63.8)stroke happened more frequently in the MeS group.Olism (P = 0.86), but prevalence of low HDL was significantly higher in females than in males (65.4 vs. 35.8 ; P < 0.001). In addition, MeS was not significantly associated with age and duration of HD and was not significantly associated with BUN, Cr, Ca, P, immunoreactive parathyroid hormone (iPTH), Alb, Hb, iron, total iron binding capacity (TIBC), ferritin, C-reactive protein (CRP), and Kt/V.Metabolic Syndrome P ValueYes (n = 151) 70 (46.4) 117 (77.5) 81 (53.6)< 0.0001 < 0.0001 0.88 c 0.007 0.43 c 0.18 cAge, yDiabetes mellitus Hypertension Low HDLC65 [20-90] 130 [80-200] 80 [50-100]65 [36-84] 130 [90-200] 80 [50-110] 106 (70.2) 102 (67.5) 25.2 ?4.2 85 (56.3) 116 (76.8) 135 (89.4)Metabolic features Systolic BP, mm HgDiastolic BP, mm HgAbnormal glucose metabolism Elevated triglycerides Abdominal obesity FBS, mmol/L Body mass index, kg/m2 Cholesterol, mmol/L HDLC, mmol/L Creatinine, mol/L Sodium, mmol/L iPTH, ng/L WBC PLT Calcium, mmol/L Hemoglobin, g/L Fe, mol/L CRP TIBC, mol/L AST, kat/L KT/V ALT, kat/L< 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 0.46 c 0.08 0.245 0.68 0.01 0.82 0.12 0.22 0.17 0.39 cSerum laboratory features4.88 [3.33-24.98] 23.56 [6.78-92.46] 777.92 ?238.68 2.56 ?.42 2.28 ?0.18 139.1 ?3.6 5.3 ?0.8 1.45 [0.43-7.55] 3.82 ?0.86 1.26 ?0.22.9 ?3.6.83 [3.05-21.15] 21.74 [6.07-89.96] 751.40 ?203.32 1.58 ?0.36 2.23 ?0.18 138.5 ?3.4 5.13 ?0.6 1.23 [0.59-5.76] 1.06 ?0.26 4.35 ?1.Triglyceride, mmol/L Potassium, mmol/LBlood urea nitrogen, mmol/LPhosphorus, mmol/L1766 ?109/L (806 ?109/L-6236 ?109/L) 1208.44 [26.90-5605] 0.30 [0.07-1.60] 0.28 [0.12-2.29] 421.75 ?93.39 48 [12-192] 26 (17.4) 14 (31.8) 5 (11.4) 44 21 (14.1) 1.18 ?0.25 41 ?6 20 [0-120] 13.60 [3.40-37.95] 52.57 ?9.108 ?2 6 ?109/L (2.76 ?109/L-12.26 ?109/L)254 [11-2000]107 ?17 6.66 ?109/L (2.56 ?109/L-15.76 ?109/L) 1806 ?109/L (676 ?109/L-5016 ?109/L) 890.07 [29.15-4232.90] 0.28 [0.08-2.29] 410.45 ?83.28 1.24 ?0.24 36 [12-144] 46 (30.5) 10 (17.9) 14 (25) 56 42 (27.8) 39 ?5 0.30 [0.08-3.52] 0 [0-120] 13.96 [4.48-39.56] 49.49 ?11.225.5 [8-1516]0.002 c 0.602 0.056 c 0.075 c 0.738 0.06 0.28 0.47 0.Ferritin, mmol/L Albumin, g/LUric acid, mol/L Duration of treatment with hemodialysis, mo History of MI Death MI History of Stroke Stroke0.412 c 0.004 0.008 0.Nephro Urol Mon. 2015;7(1):e32 (57.1) a Data are presented as mean ?SD or No. ( ) or median [range]. b Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BP, blood pressure; CRP, C-reactive protein; FBG, fasting blood sugar; Fe, iron; GIB, gastrointestinal bleeding; HDLC, high-density lipoprotein cholesterol; iPTH, immunoreactive parathyroid hormone; MI, myocardial infarction; PLT, platelet count; TIBC, total iron binding capacity; WBC, white blood cell. c Mann Whitney U test.Others (Sepsis, Cancer, Cirrhosis, Pneumonia, GIB, unknown)25 (56.8)During the study, the CHD occurred more frequently in patients with MeS (42 patients (27.8 )) than in those without MeS (21 patients (14.1 )) (P = 0.004). The rate of death due to CHD was 28.6 (12 patients) in those with MeS and 23.8 (5 patients) in those without MeS, showing no significant differences (Table 2). In addition,Variables Age, yJalalzadeh M et al.Table 3. Metabolic and Laboratory factors of Hemodialysis Patients by Gender a,bMetabolic syndrome Diabetes mellitus Hypertension Low HDLC Female (n = 127) 62.4 ?13.5 105 (82.7) 83 (65.4) 56 (44.1) 78 (61.4) 65 (51.2) 81 (63.8)stroke happened more frequently in the MeS group.