Product Name: DNASE2B antibody [N1C3]
Applications: ICC/IF, WB
Predicted Target Size: 42 kDa (note) (2)
Positive Controls: A549
Form Supplied: Liquid
Concentration: 0.91 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: deoxyribonuclease II beta
Background: The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Synonyms: DLAD antibody, DNASE2B antibody, lysosomal DNase II antibody, DNase2-like acid DNase antibody, endonuclease DLAD antibody, deoxyribonuclease-2-beta antibody, DNase II beta antibody, DNase II-like acid DNase antibody, deoxyribonuclease II beta antibody
Cellular Localization: Lysosome
CAS NO: 309712-55-8
Product: WEHI-539
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human DNASE2B. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21896658?dopt=Abstract
