Product Name: DNA-PKcs (phospho Thr2609) antibody
Applications: ELISA, ICC/IF, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.93 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: protein kinase, DNA-activated, catalytic polypeptide
Background: DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.
Synonyms: HYRC Antibody , PRKDC Antibody , DNPK1 Antibody , DNA PKCS Antibody , HYRC1 Antibody , XRCC7 Antibody , P350 Antibody , DNAPK Antibody
Cellular Localization: Nuclear
CAS NO: 429658-95-7
Product: Talarozole
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Synthetic peptide – amino acids 2604-2614 of human DNA PKcs – phosphorylated at the pT2609 residue
Antigen Species: Human
Species Reactivity: Human, Chimpanzee
Conjugation: Unconjugated
Storage Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 and 0.01% (w/v) Sodium Azide
Storage Instruction: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23425860?dopt=Abstract
