Product Name: DOCK1 antibody, C-term
Applications: WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX89965-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: dedicator of cytokinesis 1
Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.
Synonyms: dedicator of cytokinesis1, DOCK180, dedicator of cytokinesis 1, RP1182L9.1, DOCK1, RP11-82L9.1, ced5, dedicator of cyto-kinesis 1, dedicator of cyto kinesis 1
Cellular Localization: Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-triphosphate.
CAS NO: 162011-90-7
Product: AZD5363
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-TTRKQTSVDSGIVQ
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for DOCK1.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22216013?dopt=Abstract
