Product Name: DOK2 antibody
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 56 (note)
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Full Name: docking protein 2, 56kDa
Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation
Synonyms: p56DOK, p56dok-2, DOK2, p56(dok-2), docking protein 2, downstream of tyrosine kinase 2, docking protein 2, 56kDa
Cellular Localization:
CAS NO: 183133-96-2
Product: Otenabant (Hydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen: Peptide sequence around aa.297~301 (G-E-Y-A-V) derived from Human DOK2.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20384787?dopt=Abstract
