Product Name: DOK2 antibody [N1C1]
Applications: ICC/IF, WB
Predicted Target Size: 45 kDa (note)
Positive Controls: 293T , Jurkat , Raji , NCI-H929
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: docking protein 2, 56kDa
Background: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq]
Synonyms: p56DOK antibody, p56dok-2 antibody, DOK2 antibody, p56(dok-2) antibody, docking protein 2 antibody, downstream of tyrosine kinase 2 antibody, “docking protein 2, 56kDa antibody”
Cellular Localization:
CAS NO: 1035270-39-3
Product: PCI-34051
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human DOK2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20681788?dopt=Abstract