Product Name: DOK3 antibody [C3], C-term
Applications: WB
Predicted Target Size: 53 kDa (note) (3)
Positive Controls: A431
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: docking protein 3
Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function.
Synonyms: DOKL antibody, FLJ22570 antibody, FLJ39939 antibody, DOK3 antibody, docking protein 3 antibody, downstream of tyrosine kinase 3 antibody, Dok-like protein antibody
Cellular Localization: Cytoplasm , Cell membrane; Peripheral membrane protein; Cytoplasmic side , Cytoplasm , Cell membrane
CAS NO: 1433953-83-3
Product: Canertinib
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DOK3. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20715180?dopt=Abstract
