Product Name: DOT1L antibody
Applications: WB
Predicted Target Size: 185 kDa (note)
Positive Controls: *H1299
Form Supplied: Liquid
Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein A.
Full Name: DOT1-like, histone H3 methyltransferase (S. cerevisiae)
Background: Histone methyltransferase. Methylates Lys-79 of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
Synonyms: DKFZp586P1823 antibody, DOT1 antibody, KIAA1814 antibody, KMT4 antibody, DOT1L antibody, lysine N-methyltransferase 4 antibody, histone methyltransferase DOT1L antibody, H3-K79-HMTase antibody, DOT1-like protein antibody, histone H3-K79 methyltransferase antibody, “histone-lysine N-methyltransferase, H3 lysine-79 specific antibody”, “DOT1-like, histone H3 methyltransferase (S. cerevisiae) antibody”
Cellular Localization: Nucleus
CAS NO: 845614-11-1
Product: LY2835219
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DOT1L. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19221029?dopt=Abstract
