Product Name: DPYD antibody [N1N2], N-term
Applications: IHC-P, WB
Predicted Target Size: 111 kDa (note) (3)
Positive Controls: Raji , K562 , NCI-H929
Form Supplied: Liquid
Concentration: 0.59 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dihydropyrimidine dehydrogenase
Background: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. [provided by RefSeq]
Synonyms: DHP antibody, DHPDHASE antibody, DPD antibody, MGC132008 antibody, MGC70799 antibody, DPYD antibody, dihydrouracil dehydrogenase antibody, dihydropyrimidine dehydrogenase [NADP+] antibody, dihydrothymine dehydrogenase antibody, dihydropyrimidine dehydrogenase antibody
Cellular Localization: Cytoplasm
CAS NO: 82034-46-6
Product: Strontium Ranelate
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human DPYD. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17185354?dopt=Abstract
