Product Name: DR4 antibody [8Y3]
Applications: FACS
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: tumor necrosis factor receptor superfamily, member 10a
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Synonyms: TRAILR1 Antibody , APO2 Antibody , tumor necrosis factor receptor superfamily, member 10a Antibody , CD261 Antibody , DR4 Antibody , TRAILR-1 Antibody
Cellular Localization:
CAS NO: 69308-37-8
Product: INNO-206
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Human recombinant DR4 EC domain.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to detect human DR4.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18083841?dopt=Abstract
