Product Name: DR4 antibody [HS101] (Azide free)
Applications: FACS, ICC/IF, IP, Functional Assay
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G-affinity purified.
Full Name: tumor necrosis factor receptor superfamily member 10a
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Synonyms: CD261 Antibody , tumor necrosis factor receptor superfamily member 10a Antibody , APO2 Antibody , TNFRSF10A Antibody , TRAILR1 Antibody
Cellular Localization:
CAS NO: 956104-40-8
Product: Tolcapone
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant human TRAIL-R1 (DR4).
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS containing 10% glycerol.
Storage Instruction: Stable for at least 1 year after receipt when stored at -20°C.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16929168?dopt=Abstract