Product Name: DR5 antibody [10B4]
Applications: Induction
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: tumor necrosis factor receptor superfamily, member 10b
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms: KILLER/DR5 Antibody , TRICK2 Antibody , TRAILR2 Antibody , TRICK2A Antibody , KILLER Antibody , TRICKB Antibody , TRAIL-R2 Antibody , ZTNFR9 Antibody , DR5 Antibody , tumor necrosis factor receptor superfamily, member 10b Antibody , TRICK2B Antibody , CD262 Antibody
Cellular Localization:
CAS NO: 1124329-14-1
Product: MC 976
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Human recombinant TNFRSF10B EC domain
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to detect human TRAIL-R2 by direct ELISA.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16166253?dopt=Abstract
