Product Name: DR5 antibody [7F4-F8-G11]
Applications: ICC/IF, WB
Predicted Target Size: 48kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purified
Full Name: tumor necrosis factor receptor superfamily, member 10b
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily,and contains an intracellular death domain.This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand(TNFSF10/TRAIL/APO-2L),and transduces an apoptosis signal.Studies with FADD-deficient mice suggested that FADD,a death domain containing adaptor protein,is required for the apoptosis mediated by this protein.Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.[provided by RefSeq,Mar 2009]
Synonyms: TNFRSF10B Antibody , KILLER/DR5 Antibody , TRICKB Antibody , TRICK2 Antibody , TRAIL-R2 Antibody , ZTNFR9 Antibody , tumor necrosis factor receptor superfamily, member 10b Antibody , TRICK2B Antibody , CD262 Antibody , TRAILR2 Antibody , TRICK2A Antibody
Cellular Localization: Membrane;Single-pass type I membrane protein.
CAS NO: 760937-92-6
Product: 24R-Calcipotriol
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Purified recombinant human TNFRSF10B protein fragments expressed in E.coli.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16887936?dopt=Abstract
