Product Name: DR5 antibody [DJR2-4]
Applications: FACS, ICC/IF
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by affinity chromatography
Full Name: tumor necrosis factor receptor superfamily member 10b
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms: TNFRSF10B Antibody , KILLER/DR5 Antibody , TRICK2 Antibody , TRAILR2 Antibody , TRICK2A Antibody , KILLER Antibody , TRICKB Antibody , TRAIL-R2 Antibody , ZTNFR9 Antibody , tumor necrosis factor receptor superfamily, member 10b Antibody , TRICK2B Antibody , CD262 Antibody
Cellular Localization:
CAS NO: 16590-41-3
Product: MC 1046
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Extracellular domain of DR5-human IgG1 Fc fusion protein.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS, 0.09% Sodium Azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. This product may contain precipitation. Recommend microcentrifugation before use.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16432901?dopt=Abstract
