Product Name: DR5 antibody [HS201] (Azide free)
Applications: FACS, ICC/IF, IP, Functional Assay
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G-affinity purified.
Full Name: tumor necrosis factor receptor superfamily member 10b
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms: TRICKB Antibody , tumor necrosis factor receptor superfamily member 10b Antibody , TRICK2A Antibody , TRICK2 Antibody , KILLER/DR5 Antibody , TRAILR2 Antibody , CD262 Antibody , TRICK2B Antibody , TRAIL R2 Antibody , TNFRSF10B Antibody , KILLER Antibody , ZTNFR9 Antibody
Cellular Localization:
CAS NO: 1315355-93-1
Product: N-Desethyl Sunitinib
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant human TRAIL-R2 (DR5).
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS containing 10% glycerol.
Storage Instruction: Stable for at least 1 year after receipt when stored at -20°C.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16420418?dopt=Abstract
