Product Name: DUSP14 antibody
Applications:
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: IgG fraction
Full Name: dual specificity phosphatase 14
Background: In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 which interacts with B7-1 and B7-2 ligands on antigen-presenting cells. CD28 co stimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.
Synonyms: 606618, MKP6, O95147, DUSP14, MKP-L, 11072, MKPL, MKP L
Cellular Localization:
CAS NO: 630124-46-8
Product: SB-742457
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: Synthetic peptide: CEKESRHLMPYWGI from C Terminus of the protein sequence according to NP_008957.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Storage Instruction: Upon receipt – Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27101945?dopt=Abstract
