Product Name: DUSP16 antibody [C2C3], C-term
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 73 kDa (note) (2)
Positive Controls: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji
Form Supplied: Liquid
Concentration: 0.63 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dual specificity phosphatase 16
Background: The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM]
Synonyms: FLJ36298 antibody, FLJ40991 antibody, KIAA1700 antibody, MGC129701 antibody, MGC129702 antibody, MKP-7 antibody, MKP7 antibody, DUSP16 antibody, mitogen-activated protein kinase phosphatase 7 antibody, MAPK phosphatase-7 antibody, dual specificity protein phosphatase 16 antibody, MAP kinase phosphatase 7 antibody, dual specificity phosphatase 16 antibody
Cellular Localization: Cytoplasm , Nucleus
CAS NO: 911417-87-3
Product: NB-598 (Maleate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human DUSP16. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27683544?dopt=Abstract
