Product Name: DUSP26 antibody [N1C1]
Applications: ICC/IF, WB
Predicted Target Size: 24 kDa (note) (3)
Positive Controls: NT2D1 , IMR32 , U87-MG , MCF-7 , mouse brain
Form Supplied: Liquid
Concentration: 1.01 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dual specificity phosphatase 26 (putative)
Background: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Synonyms: DUSP24 antibody, LDP-4 antibody, MGC1136 antibody, MGC2627 antibody, MKP8 antibody, NATA1 antibody, SKRP3 antibody, DUSP26 antibody, DSP-4 antibody, low-molecular-mass dual-specificity phosphatase 4 antibody, mitogen-activated protein kinase phosphatase 8 antibody, MAP kinase phosphatase 8 antibody, Novel amplified gene in thyroid anaplastic cancer antibody, dual specificity phosphatase SKRP3 antibody, dual specificity protein phosphatase 26 antibody, MKP-8 antibody, dual-specificity phosphatase SKRP3 antibody, dual specificity phosphatase 26 (putative) antibody
Cellular Localization: Cytoplasm , Nucleus , Golgi apparatus
CAS NO: 160369-85-7
Product: SEA0400
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DUSP26. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27602518?dopt=Abstract
