Product Name: DUSP2 antibody [C2C3], C-term
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 34 kDa (note)
Positive Controls: HeLa
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dual specificity phosphatase 2
Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq]
Synonyms: PAC-1 antibody, PAC1 antibody, DUSP2 antibody, serine/threonine specific protein phosphatase antibody, dual specificity protein phosphatase 2 antibody, dual specificity protein phosphatase PAC-1 antibody, dual-specificity phosphatase 2 antibody, dual specificity phosphatase 2 antibody
Cellular Localization: Nucleus
CAS NO: 898044-15-0
Product: NKP608
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP2. The exact sequence is proprietary.
Antigen Species:
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27736876?dopt=Abstract
