Product Name: DYNLL1 antibody
Applications: IHC-P, WB
Predicted Target Size: 10 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purification
Full Name: dynein, light chain, LC8-type 1
Background: Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Synonyms: DLC1 Antibody , LC8a Antibody , PIN Antibody , DNCL1 Antibody , LC8 Antibody , hdlc1 Antibody , DYNLL1 Antibody , DNCLC1 Antibody , dynein, light chain, LC8-type 1 Antibody
Cellular Localization:
CAS NO: 1028385-32-1
Product: Bazedoxifene (acetate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: The immunogen sequence is the full length 89AA of human DYNLL1.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction: Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26222784?dopt=Abstract