Product Name: DYRK2 antibody
Applications: IHC, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: peptide affinity purified
Full Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Background: DYRK2, or dual specificity tyrosine-phosphorylation-regulated kinase 2, has a role in the regulation of cellular growth and/or development. In response to DNA damage, DYRK2 regulates p53 phosphorylation on Ser-46 to induce apoptosis. DYRK2 has been propos
Synonyms: Dual specificity tyrosine-phosphorylation-reg, EC 2.7.12.1 antibody, EC2.7.12.1 antibody, DYRK2, DYRK-2, Dual specificity tyrosinephosphorylationreg, DYRK 2
Cellular Localization: Cytoplasm. Nucleus. Note=Translocates into the nucleus following DNA damage.
CAS NO: 147657-22-5
Product: KU14R
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Synthetic peptide made to an internal portion of the human protein (within residues 400-500). [Swiss-Prot# Q92630]
Antigen Species: Human
Species Reactivity: Human, Chicken, Zebrafish
Conjugation: Unconjugated
Storage Buffer: Tris-citrate/phosphate, pH 7-8
Storage Instruction: Store at 4C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: DYRK2. The product does not react with mouse or rat protein.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26015562?dopt=Abstract
