Product Name: Dopamine Receptor D1 antibody
Applications: IHC-P
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Immunogen affinity purified.
Full Name: dopamine receptor D1
Background: DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinsons disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension. Dopamine receptor D1 has been reported mostly in various regions of the brain. ESTs have been isolated from normal olfactory epithelium and cancerous genitourinary tract libraries.
Synonyms: P21728, Dopamine receptor D1, DRD1A, 126449, DADR, DRD1, 1812
Cellular Localization: Cell Membrane
CAS NO: 62288-83-9
Product: Tariquidar (methanesulfonate, hydrate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: The immunogen corresponding to a region within amino acids 220 and 270 of human DRD1 (NP_000785.1).
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide
Storage Instruction: Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19574550?dopt=Abstract
