Product Name: Doublecortin antibody
Applications: WB
Predicted Target Size: 40-45 (note)
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Full Name: doublecortin
Background: Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
Synonyms: DBCN, DC, FLJ51296, LISX, SCLH, XLIS, DCX, lissencephalin-X, doublin, lis-X, neuronal migration protein doublecortin, doublecortex, doublecortin
Cellular Localization:
CAS NO: 701213-36-7
Product: Capadenoson
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen: Peptide sequence around aa.413~417( P-T-S-P-G) derived from Human Doublecortin.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19509021?dopt=Abstract
