Product Name: Dyrk3 antibody
Applications: WB
Predicted Target Size: 66 kDa (note)
Positive Controls: 293T , H1299 , HepG2 , Raji , mouse liver
Form Supplied: Liquid
Concentration: 0.68 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Background: This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Synonyms: DYRK5 antibody, RED antibody, REDK antibody, hYAK3-2 antibody, DYRK3 antibody, regulatory erythroid kinase antibody, protein kinase Dyrk3 antibody, dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5 antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 antibody
Cellular Localization: Nucleus
CAS NO: 78782-99-7
Product: NSC 42834
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Dyrk3. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25661186?dopt=Abstract