Product Name: Dystrophin antibody
Applications: IHC, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified
Full Name: dystrophin
Background: Dystrophin is one of the actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin expression is found in muscle brain tissues, where it is located to the inner surface of the plasma membrane. It is suggested that alternative splicing of the caboxy terminus allows dystrophin to interact with a variety of proteins. Loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and lack of dystrophin results in the loss of linkage between the cytoskeleton and extracellular matrix.
Synonyms: Dystrophin, DXS272, DXS269, DXS268, DXS270, DXS239, DXS142, DXS206, DXS230, CMD3B, DMD, DXS164, BMD
Cellular Localization:
CAS NO: 957890-42-5
Product: (Z)-SMI-4a
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen:
Antigen Species:
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS (pH 7.2) containing 30% glycerol and 0.01% thimerosal
Storage Instruction: The antibody solution should be gently mixed before use. Stored at -20 °C for future use.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for Dystrophin.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25899407?dopt=Abstract
