Product Name: Dystrophin antibody [1808]
Applications: ICC/IF, IHC-P
Predicted Target Size:
Positive Controls: Skeletal muscle
Form Supplied: Liquid
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G affinity purified
Full Name: dystrophin
Background: Dystrophin is a member of the spectrin/alpha-actinin family of actin-binding, triple helix rod-containing proteins. It is absent or greatly reduced in individuals with the X-linked recessive Duchennes muscular dystrophy disorder, as well as in mice with the mdx (murine muscular dystrophy) mutation.
Synonyms: Dystrophin, DXS269, DXS272, 1756, DXS268, DXS239, DXS270, DXS142, 300376, DXS206, P11532, DXS230, DMD, DXS164, BMD, CMD3B
Cellular Localization: Cell Membrane
CAS NO: 111974-72-2
Product: PRX-08066
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Acetylcholine receptor (AChR) enriched membranes and peripheral membrane proteins from Torpedo nobiliana electric organ.
Antigen Species: Human
Species Reactivity: Human, Mouse, Chicken, Rat, Xenopus laevis
Conjugation: Unconjugated
Storage Buffer: 10mM Phosphate-buffered saline, pH7.4, contianing 0.2%BSA, and 0.09% sodium azide
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Dystrophin – shows no cross-reaction with C-protein (an isoform of alpha actinin), alpha actin, or human muscle spectrin.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25978521?dopt=Abstract
