Product Name: EGFR antibody [ICR11]
Applications: FACS, IHC-Fr, IP
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1.0 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G purified
Full Name: epidermal growth factor receptor
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Synonyms: ERBB1 Antibody , HER1 Antibody , epidermal growth factor receptor Antibody , ERBB Antibody , mENA Antibody , PIG61 Antibody
Cellular Localization:
CAS NO: 32222-06-3
Product: Apremilast
Host: Rat
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: Squamous cell carcinoma
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS, 0.09% Sodium Azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. This product may contain precipitation. Recommend microcentrifugation before use.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody, clone ICR11, binds to epitope C of EGFR
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24139800?dopt=Abstract